The problem with this current strict isolation is that overall human immune system is deprived on exposure to the normal level variety of pathogen viruses and bacteria. With time the epidemiological problem will only aggravate. Infectious deceases will become more aggressive in both: spreading and effect. My prediction is that within the next 5 years as Covid-19 being in decline we will be having other much more serious infections accompanied with new possibly stricter lockdowns and prohibitions.